![]() ![]() Associated symptoms and findings typically include delays in physical development before and after birth (prenatal and postnatal growth retardation) characteristic abnormalities of the head and facial (craniofacial) area, resulting in a distinctive facial appearance malformations of the hands and arms (upper limbs) and mild to severe intellectual disability. 5 Myths About Orphan Drugs and the Orphan Drug ActĬornelia de Lange syndrome (CdLS) is a rare genetic disorder that is generally apparent at birth (congenital).COVID-19 Rapid Response Leadership Series.Information on Clinical Trials and Research Studies.
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